In vitro embryo production after melatonin administration in sheep of indigenous breeds of Greece and Hungary

In this project, the effects of exogenously administered melatonin were studied on follicular fluid composition (steroid hormones concentration, plasminogen-plasmin activity), on oocyte quality and on in vitro embryo production, during seasonal anestrus. Moreover, the effects of melatonin treatment on the ovarian response to superovulation regimes were studied by assessing the follicular population, the quality of ova and the composition of follicular fluid collected

Duration: 2005-2007
Funded by: General Secretariat of Research and Technology (Bilateral Cooperation Greece-Hungary 2005-2007)
Project Leaders: Dr. GS Amiridis, Prof. S Cseh
  • University of Thessaly, Faculty of Veterinary Medicine, Clinic of Obstetrics & Reproduction
  • NAGREF, Veterinary Research Institute (Thessaloniki)
  • NAGREF, Agricultural Research Station, (Chalkidiki)
  • TEI of Larissa, Department of Animal Production 
  • Department of Obstetrics & Reproduction, Faculty of Veterinary Science, Saint Stephan University, Budapest
  • Ceva Hellas Ltd
  • Awasi Corporation, Hungary


Publication of project results:

  • Melatonin improves the developmental competence of sheep oocytes. E Valasi, Th Tsiligianni, Th Papanikolaou, I Dimitriadis, E Vainas, F Samartzi, GS Amiridis. 2006. 10th Annual Conference of the ESDAR, Portoroz (Poster P126), Reproduction in domestic animals, Vol 41 (4), p. 341.
  • Effects of melatonin treatment on follicular development and oocyte quality in Chios ewes. Th Tsiligianni, I Valasi, S Cheh, E Vainas, V Faigl, F Samartzi, Th Papanikolaou, E Dovolou, GS Amiridis. 2009. Acta Veterinaria Hungarica, Vol 57 (2), p. 331-335.
  • Ανάπτυξη ωοθυλακίων και ποιότητα ωαρίων μετά από χορήγηση μελατονίνης σε προβατίνες στην άνοιστρη περίοδο. Βαλάση Ε, Τσιλιγιάννη Θ, Ντόβολου Ε, Βαϊνάς Ε, Faigl V, Παπανικολάου Θ, Σαμαρτζή Φ, Cseh S, Αμοιρίδης ΓΣ. 2011. 2ο Πανελλήνιο Συνέδριο Κτηνιατρικής παραγωγικών ζώων, Υγιεινής και Ασφάλειας τροφίμων Ζωικής Προέλευσης, Προστασίας του Καταναλωτή, Θεσσαλονίκη, Πρακτικά σ. 125.